IOWA ONCOLOGY RESEARCH ASSOCIATION
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Gynecology Cancer Research Studies

CERVICAL
G0127V   A Phase II Evaluation of ABI-007 in the Treatment of Persistent or Recurrent Squamous or Non-Squamous Cell Carcinoma of the Cervix

G0240   A Randomized Phase III Trial of Cisplatin Plus Paclitaxel with and without NCI-Supplied Bevacizumab Versus the Non-Platinum Doublet, Topotecan Plus Paclitaxel, with and without NCI-Supplied Bevacizumab, in Stage IVB, Recurrent or Persistent Carcinoma of the Cervix

R0724   Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy

OVARIAN
G0126T   A Phase II Evaluation of Belinostat and Carboplatin in the Treatment of Recurrent or Persistent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

G0212   A Randomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or CT-2103 Vs No Treatment Until Documented Relapse on Women with Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer who Achieve a Complete Clinical Response to Primary Platinum / Taxane Chemotherapy

G0213   A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel Alone or in Combination with Bevacizumab Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer

G0252   A Phase III Clinical Trial of Bevacizumab with IV Versus IP Chemotherapy in Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma

ENDOMETRIAL
G0229H   A Phase II Evaluation of AZD6244 in the Treatment of Recurrent or Persistent Endometrial Carcinoma (temporarily suspended)

G0086P   A Three Arm Randomized Phase II Study of Paclitaxel / Carboplatin / Bevacizumab, Paclitaxel / Carboplatin / Temsirolimus and Ixabepilone / Carboplatin / Bevacizumab as Initial Therapy for Measurable Stage III or IVA, Stage IVB, or Recurrent Endometrial Cancer 

G0249   Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed by Paclitaxel / Carboplatin in Patients with High-Risk, Early Stage Endometrial Cancer

G0258   A Randomized Phase III Trial of Cisplatin and Tumor Volume Directed Irradiation Followed by Carboplatin and Paclitaxel Vs. Carboplatin and Paclitaxel for Optimally Debulked, Advanced Endometrial Carcinoma

LEIOMYOSARCOMA
G0250   A Randomized Phase III Evaluation of Docetaxel and Gemcitabine Plus G-CF with Bevacizumab Vs Docetaxel and Gemcitabine Plus G-CSF with Placebo in the Treatment of Recurrent or Advanced Leiomyosarcoma of the Uterus

UTERINE
G0238   A Randomized Trial of Pelvic Irradiation with or without Concurrent Weekly Cisplatin in Patients with Pelvic-Only Recurrence of Carcinoma of the Uterine Corpus

CARCINOSARCOMA
G0261   Randomized Phase III Trial of Paclitaxel Plus Carboplatin Versus Ifosfamide Plus Paclitaxel in Chemotherapy-Naive Patients with Newly Diagnosed Stage I-IV Persistent or Recurrent Carcinosarcoma (Mixed Mesodermal Tumors) of the Uterus

CANCER CONTROL
G0256   A Prospective Study of Cognitive Function During Chemotherapy for Front-Line Treatment in Ovarian, Primary Peritoneal or Fallopian Tube Cancer

G0259   Nurse-Delivered WRITE Symptoms© vs. Self-Directed WRITE Symptoms© vs. Care as Usual for Optimal Symptom Management for Women with Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

N08CA   Use of Glutathione (GSH) for Prevention of TAXOL / CBDCA Induced Peripheral Neuropathy: Phase III Randomized Double-Blind, Placebo-Controlled Study