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Gastrointestinal Research Studies
HEPATOCELLULAR
E1208 A Phase
III Randomized, Double-Blind Trial of Chemoembolization with or without
Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and
without Vascular Invasion
N0745 Phase
I / II Randomized Trial of Sorafenib and Bevacizumab as First-Line Therapy in
Patients with Locally Advanced or Metastatic Hepatocellular Carcinoma (temporarily
suspended)
METASTATIC COLORECTAL
C80405 A Phase III Trial
of Irinotecan / 5-FU / Leucovorin or Oxaliplatin / 5-FU / Leucovorin with
Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and
Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or
Rectum
N054C Phase II Study of
Sorafenib / Bevacizumab as Salvage Therapy in Patients with Metastatic
Colorectal Cancer (temporarily suspended)
ESOPHAGEAL
N0747
A Randomized Phase II Trial of Sunitinib Plus Capecitabine Versus Capecitabine
Alone (with the potential for crossover) for Elderly and/or Poor Performance
Status Patients with Adenocarcinoma of the Esophagus or Gastroesophageal
Junction
R0436
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel,
Cisplatin, and Radiation for Patients with Esophageal Cancer who are Treated
Without Surgery
ADJUVANT COLON
E5202 Randomized
Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin VS 5-FU, Leucovorin,
Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk
for Recurrence to Determine Prospectively the Prognostic Value of Molecular
Markers
RC0948 The Oncotype
DX® Colon Cancer Assay for Stage II Colon Carcinoma: Does it Impact
Physician Adjuvant Treatment Decision Making and Patient Satisfaction?
SMALL BOWEL
N0543 A Phase
II Trial of Pharmacogenetic-Based Dosing of Irinotecan, Oxaliplatin &
Capecitabine as First-Line Therapy for Advanced Small Bowel Adenocarcinoma
RECTAL / ANAL
R-04 Clinical Trial
Comparing Preoperative Radiation Therapy and Capecitabine with or without OXAL with Preoperative
Radiation Therapy and Continuous Intravenous Infusion (CVI) of 5-Fluorouracil
(5-FU) with or without OXAL in the Treatment of Patients with Operable Carcinoma of the Rectum
PANCREATIC
N064A Phase
II Study of Panitumumab, Chemotherapy and External Beam Radiation in Patients
with Locally Advanced Pancreatic Cancer
N064B Randomized
Phase II Trial of Panitumumab, Erlotinib and Gemcitabine vs. Erlotinib and
Gemcitabine in Patients with Untreated, Metastatic Pancreatic Adenocarcinoma
R0848 Phase
III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for
Patients with Resected Head of Pancreas Adenocarcinoma
CHOLANGIOCARCINOMA
S0809 A
Phase II Trial of Adjuvant Capectibine / Gemcitabine Chemotherapy Followed by
Concurrent Capecitabine and Radiotherapy in Extrahepatic Cholangiocarcinoma
(EHCC)
CANCER CONTROL
P-5 Statin
Polyp Prevention Trial in Patients with Resected Colon Cancer
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