IOWA ONCOLOGY RESEARCH ASSOCIATION
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Brain Cancer Research Studies

NEWLY DIAGNOSED
R0825    Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide Plus Bevacizumab Versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma

RECURRENT
N0272    Phase II Trial of Imatinib Mesylate; (Gleevec; STI-571) in Treatment of Recurrent Oligodendroglioma and Mixed Oligoastrocytoma

N0572    A Phase I/II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma

N0776    Phase II Trial of Avastin in Combination with Sorafenib in Recurrent Glioblastoma Multiforme (temporarily suspended)

N0779    Phase II Study of Vorinostat (SAHA) in Combination with Bortezomib (PS-341) in Patients with Recurrent Glioblastoma Multiforme

METASTATIC
N0574    Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases