IOWA ONCOLOGY RESEARCH ASSOCIATION
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Gastrointestinal Research Studies

PANCREATIC
R0848   Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

COLORECTAL
E7208   A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab (IMC-1121B), in Advanced, K-ras Wild-type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy (temporarily suspended)

MORAb-004-202   A Randomized, Double-Blind Study of the Efficacy and Safety of Monotherapy MORAb-004 Plus Best Supportive Care in Subjects with Chemorefractory Metastatic Colorectal Cancer (temporarily suspended)

RECTAL
N1048   A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation Vs Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision

ESOPHAGEAL
R1010   
A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma

ADJUVANT COLON
C80702   A Phase III Trial of 6 Versus 12 Treatment of Adjuvant FOLFOX Plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer

CANCER CONTROL
P-5   Statin Polyp Prevention Trial in Patients with Resected Colon Cancer

WFU-99311   Randomized Placebo-Controlled Phase 2 Pilot Study of Memantine (Namenda) for Smoking Cessation Among Cancer Survivors